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Description

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This approach accelerates drug discovery and expands therapeutic options for clinical application

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However, there are also secondary pharmacology effects due to the diverse actions of these two hormones such that effects on autonomic nerve activity and hepatic glucose production through gut and portal GLP-1, effects on islet hormone secretion and islet inflammation through intra-islet effects, and effects through other mediators apart from GLP-1 (145147)

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