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doi: 10.1016/j.jamda.2024.105331 266

The substance is not only involved in energy metabolism , but also has a major protective function against oxidative stress

All patients were admitted to the ICU

Coffee enemas are known to cause the following problems: Cramps Nausea Diarrhea Rectal Burns Rectal Puncture Vomiting Bloating Bowel Perforation Dehydration Long-term risks from frequent use of coffee enemas include: Colitis an inflammation of the lining of the colon Proctocolitis an inflammation of the rectum Severe dehydration and electrolyte imbalance Septicemia also called sepsis (blood poisoning) The National Cancer Institute reports three known deaths from coffee enemas: two from electrolyte imbalances and one from septicemia (blood poisoning)