Compared with those in nonobese patients, the serum levels of the antioxidant substances MDA, SOD, GSH, and GPX were significantly greater in the obese PCOS group (160)
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Furthermore, upon extensive evaluation of the downstream signaling of TGF-Beta 2, it was found that compared to nondiabetic mice, diabetic mice have increased expression of certain cardiac proteins, such as p-p38, a protein kinase activated by genotoxic stress [30], and even gene expression, such as connective tissue growth factor (CTGF), or CTGF which is involved in multiple pathologies [31]
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