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every 2 weeks (which some patients prefer) Infliximab the first anti-TNF- drug that became available a chimeric monoclonal antibody containing 25% mouse, 75% human I g G 1 that binds to soluble & membrane bound TNF- generally it is not given as monotherapy because patients can develop a tolerance or decline in efficacy due to the development of inactivating anti-chimeric antibodies (HACA) when infliximab is given without other immunosuppressant drugs

How GHK-Cu GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a tripeptide naturally found in human blood, saliva, and urine

Each comparison has different risk profiles and potential benefits that are worth understanding before making decisions about combination therapy