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By highlighting these similarities, our research sheds light on the pathophysiology of muscular laminopathy and underscores the importance of zebrafish models in studying these complex disorders

Recent Phase 3 data showed average weight reduction exceeding 28% in some participant groups after extended treatment periods

Finally, RWS consistently reported better cardiovascular and renal outcomes of users of GLP-1RAs as compared to DPP-4 inhibitors users, and highlights the needs for further RWS comparing GLP-1RAs and SGLT-2i (and their combinations) on cardiovascular outcomes, that should eventually be confirmed by dedicated RCTs

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