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Clinicians must navigate administrative processes that require detailed documentation, justification, and, in some cases, repeated submissions

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However, the discovery of functional extrinsic death receptor-mediated eryptosis and necroptosis of erythrocytes associated with the necrosome formation opens new horizons for our understanding of the possible role of caspases in mature erythrocytes, since caspase-8 might be involved in coordinating the cell fate of mature erythrocytes

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