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Beneficial effects of betaine: a comprehensive review

Dark circles have two primary causes that are frequently conflated but require different active responses: vascular pooling in the blood vessels around the eye, which produces a bluish-purple discolouration most visible through thin skin in that area, and surface pigmentation from UV exposure, post-inflammatory marks, or accumulated melanin, which produces a brownish discolouration

Rendeiro AF, Casano J, Vorkas CK, Singh H, Morales A, DeSimone RA, et al

Untreated hypertensive patients had established hypertension defined by as seated systolic and/or diastolic blood pressure above 140 and/or 90 mm Hg, respectively, during at least two separate measurements