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In the study, participants with a responsive genetic score had an 82% increase in the likelihood of acheiving weight loss with a GLP-1 medication.[ref] Another study showed that GLP1 receptor variants are associated with greater weight loss on GLP-1 RA drugs.[ref] Common genetic variants in the GLP1R (GLP-1 receptor) gene impact weight and type 2 diabetes risk

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Members with type 2 diabetes may need support to understand how GLP-1s might fit into their personal treatment plan and what to expect when taking this type of treatment

Furthermore, alongside the increasing prevalence of related cardiometabolic diseases such as diabetes, obesity and chronic kidney disease (CKD), the number of people with HF has increased to around 64 million globally, amongst whom most are also living with type 2 diabetes or obesity ( Within the past 2 decades, glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) have emerged as effective agents to improve glycaemic control in type 2 diabetes and to reduce body weight in people with overweight or obesity (Sattar et al., 2021