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Functional enrichment (GO/KEGG) and Gene Set Enrichment Analysis (GSEA) revealed that GGCT knocking down significantly impacted pathways related to the cell cycle, oxidative stress, cell proliferation, and cell death in both cancers (Fig

The human samples were collected by Red Cross blood donor service and Aurea biobank according to ethical permits of the biobanks and shared based on research collaboration to this study

Comparing the effects seen here to a model using a melatonin-competent mouse, for example from the CBA strain, would be beneficial for future studies that consider in more detail the phasing of melatonin treatment in vivo

Clinical trials have demonstrated that tofacitinib exhibits differential efficacy in inflammatory bowel diseases