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Bacteroides thetaiotaomicron and Lactobacillus johnsonii generate fatty acids, particularly oleic acid and palmitic acid, regulate inflammatory immune responses, and eliminate Candida glabrata in the DSS-induced colitis mouse model ( Current antifungal drugs Currently, the first-line clinical antifungal drugs include polyenes (e.g., amphotericin B), azoles (e.g., fluconazole) and echinocandins (e.g., caspofungin) (Wiederhold, 2017