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While B12 injections are generally safe, some individuals may experience minor side effects, such as: Pain or swelling at the injection site Mild diarrhea Dizziness or headache Rare allergic reactions, including rash or difficulty breathing Severe side effects are uncommon
(Joshi et al., 2023)Wen et al
The FDA also categorizes which bulk drug substances compounders may use when creating custom medications, and in late 2023, the agency flagged 19 popular peptides BPC-157, TB-500, and others as Category 2 (an FDA designation for bulk drug substances that present significant safety concerns and may no longer be used in compounding), effectively banning them from traditional compounding
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