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In-use stability testing is required for multi-dose nasal sprays to demonstrate that the product remains safe and effective from first use to the last actuation including the microbiological stability of the opened container with repeated sampling

However, after 1 month, single-colored areas (SCA) appeared, generated from a single cell or neighboring cells of the same color

Finally, amelioration of the G/F-actin ratio restores the disruption of the YAP signal induced by high glucose and upregulates the transcription factors Neurod1, Foxa1, and Foxa2, which are responsible for controlling L-cell differentiation [30] (Fig

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