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In studies of non-alcoholic fatty liver disease, RSV was found to decrease the expression of lipogenic genes and triglyceride levels by attenuating NRF2 promoter methylation induced by high-fat diets and high glucose treatments, while also modulating NRF2 signaling pathways [153]

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Cascade J Neuroinflam 8:129 Funding Authors acknowledge Science and Engineering Research Board for sanctioning the fellowship grant (PDF/2017/000984) to support financially

The resulting oxaloacetate can be used to fill up (anaplerosis) the TCA cycle or diverted into the gluconeogenic pathway to glucose