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Meyer, INRES-Chemical Signalling, University of Bonn, Friedrich-Ebert-Allee 144, 53113 Bonn, Germany e-mail: [email protected] This article was submitted to Plant Cell Biology, a section of the journal Frontiers in Plant Science

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Clinical trials (STEP programme) have demonstrated significant weight loss, with participants losing an average of 12-15% of their initial body weight over 68 weeks when combined with lifestyle interventions