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DLin-MC3-DMA was integral to the development of the first FDA-approved siRNA drug, Onpattro, and has been proven effective for mRNA delivery in vivo

Considering that the use of metformin and simvastatin led to increased apoptosis and decreased mitochondrial membrane potential in glioma cell lines, we speculate whether these two drugs cause DNA damage in glioma cells

Dopamine beta hydroxylase (DBH), an enzyme that plays a central and critical role in the catecholamine biosynthetic pathway, regulates the concentrations of dopamine and norepinephrine, whose deficiency or overproduction causes several diseases related to the brain and the heart