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LA increases adipose triacylglycerol lipase (ATGL) and decreases FAS, thereby reducing TG levels

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In PD, the degeneration of dopaminergic neurons in the substantia nigra leads to an imbalance, with increased cholinergic activity contributing to motor symptoms like tremor and rigidity

Hollander PA, Levy P, Fineman MS et al (2003) Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial