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One-way analysis of variance was used for the BDNF analysis in vitro and in vivo , followed by Fisher post hoc tests

The experimental autoimmune encephalomyelitis (EAE) or lipopolysaccharide (LPS)-induced MS effectively recapitulate the inflammatory response, mitochondrial dysfunction, and oxidative stress (Wang et al., 2017

These findings are further supported by two additional systematic reviews and meta-analyses, both highlighting the favorable impact of GLP-1 RAs on functional hypogonadism, largely attributable to weight loss [174,175]

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