However, individual responses vary, so ongoing monitoring of hormone levels and potential adverse effects is essential
In addition to non-HLA Abs induced by an alloimmune mechanism, Abs directed to self-antigens, such as angiotensin II type 1 receptor (AT1R), perlecan, endothelin type A receptor (ETAR), vimentin, or Rho GDP-dissociation inhibitor 2 (ARHGDIB), have been found to be associated with inferior graft outcome, although their causal role in the pathogenesis of damage is unclear (29, 30)
A recent study revealed that mitochondrial metabolic kinase PCK2 phosphorylates and activates ACSL4, driving phospholipid remodeling linked to ferroptosis
Potential benefits: powerful inflammation control, gut barrier support, improved autoimmune balance, and skin healing/anti-inflammatory benefits