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Ricci G, Del Boccio G, Pennelli A, Lo BM, Petruzzelli R, et al

Peripheral vs Central Action AOD-9604 functions exclusively through peripheral mechanisms in adipose tissue rather than through central nervous system pathways that regulate appetite

The study of nearly 28,000 23AndMe users who reported taking the weight-loss drugs found that a mutation in GLP1R, the gene for the protein targeted by GLP-1 drugs, is modestly but significantly associated with increased efficacy of the medications, researchers reported in Nature

However, the length of time may be adjusted based on how well the treatment works for the individual and whether any side effects are experienced