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Our previous studies revealed the essential role of HGF in mechano-biology of postnatal muscle growth and regeneration centered on resident myogenic stem satellite cells, which are positioned between the basal lamina and the sarcolemma of postnatal myofibers and normally found in a mitotically and metabolically quiescent or near-dormant state (protracted G 1 phase, also referred to G 0 ) in adult muscle

5a) The source of ROS and the mechanism by which these ROS drive possibly drive this proinflammatory phenotype therefore warrant further investigation

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