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However, because IGF-1 promotes cell growth and inhibits apoptosis , it may accelerate the progression of existing or dormant tumors

That is the difference between the protocol working and the protocol failing

Thereafter, twenty minutes later, status epilepticus characterised by tonic and clonic convulsions, were induced to mice by intraperitoneal injection of pilocarpine (360 mg/kg) except the normal and positive control group which received the piracetam