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NHS prescribing guidelines follow NICE recommendations (NG28), which specify that GLP-1 receptor agonists should be considered for adults with type 2 diabetes who have inadequate glycaemic control despite optimal treatment with other agents, and who meet specific criteria including BMI thresholds or where weight loss would benefit obesity-related comorbidities

For example, whether combining ferroptosis inhibitors with anti-fibrotic agents (e.g., TGF- inhibitors and pirfenidone) yields synergistic effects remains untested, as does the potential for antagonism between these agents

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