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Keywords Near-infrared II Glutathione-ActivatedFluorescent probe Intraoperative tumor imaging Lung Metastatic Diagnosi Malignancies, characterized by the uncontrolled growth of cancer cells and a high risk of metastasis, present a significant threat to human life and health [1], [2], [3]

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In each case, a slight change in the drugs target protein prevents binding without abolishing its normal function