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Finnigan LEM, Cassar MP, Koziel MJ, Pradines J, Lamlum H, Azer K, et al
Tirzepatide activates GIP and GLP-1 receptors, slowing gastric emptying by up to 70% compared to normal digestion, which allows food to ferment and produce hydrogen sulfide gas
Six weeks of GLP-1 infusion resulted in significant improvements in fasting (decrease of 4.3 mM glucose) and 8 h mean glucose (decrease of 5.5 mM), fasting and mean 8h free fatty acids, a reduction in HbA1c from 9.2% to 7.9%, a decrease in fructosamine from 349 uM to 282 uM, and a reduction in gastric emptying 3,4
Visceral fat targeting peptides like tirzepatide show strong metabolic benefits beyond simple weight reduction
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