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Occasional mild vomiting may happen, but repeated vomiting requires attention

Endogenous acylated ghrelin serves as a gastric sensor and increases appetite and food intake, which indicates that ghrelin acts as a physiologic hunger signal (84)

This matters especially for cancer patients, as GHK-Cu may even increase cancer progression risk

In vivo, plasma half-life has been measured at 78 minutes suggesting that in the body, DSIP may complex with carrier proteins that protect it from rapid degradation, or exist as a component of a larger precursor molecule (whose gene and structure have not yet been identified)