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Specifically, analyzed were the affected brain areas (04), cerebral (NTP-7, Level 3), cerebellar cortex (NTP-7, Level 6), and hippocampus, thalamus, and hypothalamus (NTP-7, Level 3) as follows (score 0 indicates no histopathologic change): score 1: small, patchy, complete, or incomplete infarcts (10% of the area affected)

Greater weight loss correlated with greater improvement in overall quality of life scores

The compound requires subcutaneous administration for maximum bioavailability, as oral administration results in poor absorption due to first-pass metabolism

PUVA inhibits DNA replication, but not gene transcription ay nonlethal dosages