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For example, it has demonstrated pro-estrogenic effects on bone and anti-estrogenic effects on breast tissue, although its safety in women with breast cancer has not yet been confirmed

Molsberry S, Bjornevik K, Hughes KC, Zhang ZJ, Jeanfavre S, Clish C, et al

Glutathionylated proteins occur mainly in intracellular space because GSH is located in the cytoplasm and Cys residues of proteins are in a reduced form and able to form mixed disulfides