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This decline isn't just about aesthetics, like the appearance of fine lines or a loss of skin elasticity

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(2022) demonstrated that PCs treatment effectively reduces NF-Bp65 nuclear translocation and NLRP3 inflammasome activation, thereby inhibiting excessive NF-B pathway activation due to high in sugar and fat

Corticosteroids, such as prednisone and budesonide, are frequently used for moderate to severe UC, especially when 5-ASA is insufficient to manage symptoms [161]