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269 The benefits of TZDs in MASLD and fibrosis may be the increased adiponectin levels and the adiponectin-mediated effect on insulin sensitivity and hepatic fatty acid metabolism 270 and the downregulated fibrogenic factors and related pathways, inflammatory pathways like JAK/STAT and NF-B signaling pathways

Avoid treatment if the client is pregnant, breastfeeding, immunocompromised, or has known hypersensitivity to any ingredients

In a double-blind RCT, individuals using NAC 400 mg twice daily had a lower relapse rate than those taking a placebo while decreasing prednisolone [70]

Side effects, such as mild stomach upset, can make an appearance