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Risk of Infection This is the most serious concern, particularly with multi-use vials of compounded tirzepatide

Pharmacokinetics (How Long They Last): Semaglutide: Half-life: Approximately 7 days Reaches steady state: After 4-5 weeks Duration of action: Remains active for one week between doses Time to peak concentration: 1-3 days after injection Tirzepatide: Half-life: Approximately 5 days Reaches steady state: After 4 weeks Duration of action: Remains active for one week between doses Time to peak concentration: 8-72 hours after injection Both medications are designed for once-weekly dosing and maintain therapeutic levels throughout the week

Practice stress management techniques Manage stress through deep breathing exercises, regular physical activity, adequate sleep (7-9 hours nightly), and relaxation techniques like meditation or yoga

Crowded optic nerve heads are also a risk factor for NAION