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Mechanisms include a decline in the level of thyroid hormones that promotes compensatory increases in TSH secretion from the pituitary gland

Research on histopathological alterations in the liver, kidney, and gastrointestinal system has verified the safety of this treatment

BPA exposure was associated with lower total thyroxine (TT4) and free triiodothyronine (fT3) concentrations, BPS exposure with lower TSH in boys, and BPAF exposure with higher TT3 and fT3, particularly in girls

These discrepancies emphasize the necessity for standardized clinical protocols and biomarker-driven strategies to identify sub-groups that are likely to respond favorably