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Furthermore, the initial phase of rapid weight loss often coincides with the period when side effects like nausea or fatigue might be most pronounced 31 , potentially hindering a person's ability to start or maintain consistent strength training and ensure adequate protein intakethe very strategies needed to protect muscle

Glucagon-like peptide 1 (GLP-1) agonists not only exert a beneficial systemic effect, but also cross the blood-brain barrier (Kastin et al., 2002

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No robust clinical trials have been conducted specifically examining semaglutide's efficacy in managing fibromyalgia symptoms, and it is not included in any UK or international fibromyalgia treatment guidelines