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Time zone changes: Time zone changes can also disrupt your dosing schedule and cause delayed or missed doses Unpredictable lodging fridges: Hotel or Airbnb refrigerators may be too warm or too cold, which may damage the medication

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Khera AV, Wang M, Chaffin M, Emdin CA, Samani NJ, Schunkert H, Watkins H, McPherson R, Erdmann J, Elosua R, Boerwinkle E, Ardissino D, Butterworth A, Di Angelantonio E, Naheed A, Danesh J, Chowdhury R, Krumholz H , Sheu W, Rich S, Rotter J, Chen Y, Gabriel S, Lander E, Saleheen D, Kathiresan S

Lysine residues within proteins are methylated using S-adenosylmethionine (SAM) as the methyl donor