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Notably, participants in the 12mg group had not reached a weight loss plateau at 48 weeks, suggesting that longer treatment durations could yield even greater reductions

Human clinical trials establishing these effects have not been completed and conclusions about efficacy in humans should not be drawn from this data alone

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In this cycle, it serves as a cofactor to allow conversion, so a deficiency of B12 or folate can interfere with the conversion and lead to a buildup of homocysteine 1