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The oral route reduces potential adverse events associated with intravenous (IV) administration but is associated with low bioavailability
To mitigate these effects, plants activate sophisticated antioxidant defense networks involving enzymes such as superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX), and glutathione peroxidase (GPX), as well as non-enzymatic antioxidants, including phenolics, flavonoids, anthocyanins, and lignin (Fujita and Hasanuzzaman 2022)
ISSN 2161-3362
The diagnosis usually involves the following: clinical findings, the finding of 5-oxoprolinuria, low levels of glutathione, low activity of glutathione synthetase, and mutation analysis of the glutathione synthetase gene
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