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Shuxiao, symptoms that warrant professional evaluation include: Burning or pain while urinating Blood in the urine Inability to hold in urine Bleeding from the vagina or vulva Abnormally long or heavy periods Abnormally long time between periods or missing periods Abnormally foul or fishy vaginal odor Symptoms that transfer to sexual partners New ulcers, warts, or wounds on the vulva or vagina Pain in the vulva, vagina, or pubic area A healthcare provider can help determine whether these symptoms are related to Ozempic or another underlying condition and guide you toward the right treatment

Total RNA was extracted from cell samples using TRIzol (Invitrogen)

doi:10.3390/ijerph18031243 69

at 2025C (typical room temperature), degradation accelerates to 3040% loss in the same timeframe