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Five days after DSS treatment, the number of active neuronal cells in the DVN, NST, and CeA increased in the brain of the Con-DSS group, revealing that the control mice felt extensive visceral discomfort (Fig

Scientific editor: Dr

& Liu, P

Acknowledgments Figure was Created in Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest