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Hydrogels Hydrogel is a type of polymer characterized by its three-dimensional network structure formed through the cross-linking of the polymer backbone and hydrophilic functional groups via covalent bonds, ionic bonds, hydrogen bonds, or physical entanglement [94]

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Unlike apoptosis, which involves caspase activation and nuclear fragmentation, ferroptosis is initiated by iron accumulation and lipid peroxidation, resulting in membrane rupture without caspase involvement (13)