tirzepatide renal impairment Kidney Parameters with in Obesity... : Journal of the American Society of Nephrology Effect of tirzepatide on albuminuria

[23] Orlistat should not be used during pregnancy or in people with chronic malabsorption syndrome or cholestasis

Bazhan N, Jakovleva TV, Kazantseva AY, Kostina NE, Orlov PE, Balybina NY, Baranov K, Makarova EN

These findings suggest that current GLP-1 RA trial designs may contribute to lower estimated trial-eligible proportions among Asian populations, which could in turn limit the generalizability of trial results to these groups

Serious side effects such as pancreatitis and gallbladder problems are uncommon, but patients should know the warning signs and seek medical advice if symptoms are severe, persistent or unusual