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If youve been trying to lose weight, youll almost certainly have heard of Semaglutide by now

3,36,37 On the other hand, keratinocytes may also produce IL-23 via the actin polymerising molecule N-WASP demethylating the histone H3K9 that controls IL-23 expression

CagriSema (cagrilintide + semaglutide) CagriSema is the most directly comparable combination because it also pairs cagrilintide with a GLP-1 agonist