glp 1 and muscle pain Study finds GLP-1 receptor agonists target fat over for weight loss Glucagon-like peptide-1 receptor agonists in

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Methods The current study involves the fusion of a native or mutant GLP-1 (30 residues) with an HSA-binding DARPin (123 residues) via a rigid helical linker (15 residues) to create fusion proteins (168 residues) resistant to DPP-IV and, or trypsin with extended half-lives using structural modeling, which are subsequently characterized using MD simulation and molecular docking analyses