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doi: 10.1067/mcp.2000.104736

For 5 mg/mL, add 12 mL

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This distinction is maintained throughout the manuscript to avoid conceptual dilution and to clearly differentiate between true circadian entrainment and indirect modulation of circadian function ( Age-related declines in melatonin secretion and signaling have been consistently associated with circadian rhythm dampening, sleep fragmentation, increased oxidative stress, and chronic low-grade inflammation, all hallmarks of biological aging