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J Am Acad Dermatol 2010

Dietary Se intake clearly differs between regions of the world, largely due to the variable Se content of soil, as well as pH, redox, and water content of the soil, which all influence the Se uptake by growing plants, and consequently, animals exposed, as well as water and the type of food consumed by humans (45, 69)

(2023) 83:45704585.e7

So, perhaps the way GLP-1 normally works is that we eat a meal, and GLP-1 sends the appetite-reducing signal to our brain directly through the vagus nerve