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The Recommended Dietary Allowance for iodine is significantly increased during pregnancy, from 150 to 220 micrograms/day

Khanna S, Walia S, Kondepudi KK, Shukla G (2020) Administration of indigenous probiotics modulate high-fat diet-induced metabolic syndrome in sprague dawley rats

The 12 month percentage change for this period was 3.2%

This often involves dose titration a process in which the dose of medication is gradually increased over days, weeks or sometimes months to achieve the optimal therapeutic effect while minimizing side effects