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(2) To investigate this, the researchers studied in depth the apparent disruption of FOXO4p53 binding and suggested that by disrupting it, the FOXO4-DRI peptide may shift p53 trafficking toward the mitochondria

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To test whether plasma purine and monoamine metabolite concentrations were correlated in SZ, we studied previously published measurements (Yao et al., 2010a, b) of six purine metabolites (Hx, Xan, Xant, G, Gr, UA) for which concomitant measurements of 14 monoamine metabolites, tryptophan (TRP), serotonin (5-hydroxytryptamine, 5-HT), 5-hydroxyindoleacetic acid (5-HIAA), tryptamine (TRPA), melatonin (MEL), kynurenine (KYN), 3-hydroxykynurenine (3-OHKY), tryptophol (TPOL), tyrosine (TYR), L-3,4-dihydroxyphenylalanine (L-DOPA), Normetanephrine (NMET), homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylglycol (MHPG), and vanillylmandelic acid (VMA), were also available from HC ( n = 30) and FENNS-BL ( n = 25) and FENNS-4w ( n = 25)