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These disorders are characterized by mtDNA mutations that impair mitochondria electron transport chain enzyme complexes, which can result in increased ROS production, oxidative damage, and decreased ATP production (Quintana et al., 2010

Removal of bioactive GLP-1 is a consequence of N-terminal proteolysis catalyzed by dipeptidylpeptidase IV (DPP IV or DPP4)

Stimulation of whole blood cells from SZ patients with selective TLR agonists results in enhanced release of pro-inflammatory cytokines (including IL-1, IL-6, IL-8, and TNF-) (150), further supporting the role of TLRs in regulating neuroinflammation in schizophrenia

Pregnant or nursing women, children under 18 and individuals with known medical conditions should consult their physician prior to taking.