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Another strength is the use of MR analysis, a method able to overcome common sources of bias in observational studies, such as residual confounding and reverse causality

Rinaman said that her laboratory discovered that the GLP-1 neurons in the rodent hindbrain are suppressedthat is, their ability to be activated is reducedduring states of negative energy balance, for example, after 18 hours of fasting in rats or mice (Maniscalco and Rinaman, 2018)

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