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Compounds inhibiting intracellular melanosome transport or activating melanosome degradation have been explored in recent years

Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation

Interestingly, Daf-16/FoxO and mTOR factors have significant immunoregulatory effects via the STAT3 signaling pathways (see below)