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Selected candidates were women who were diagnosed with uterine leiomyoma based on transvaginal ultrasounds, and had a fibroid at least 8 cm or more, less than 4 uterine fibroids and just one type of fibroid (either submucosal, intramural or subserosal), with no pedunculated fibroids, were premenopausal, not pregnant, had not taken hormonal medications in the previous 6 months and no hormonal medication for their fibroids in the past 3 months and did not have certain diseases that were listed as exclusionary criteria

Additionally, we manually searched the websites of the European Association for the Study of Diabetes and American Diabetes Association scientific meetings, as well as ClinicalTrials.gov, to retrieve additional qualified trials or search the database for any additional information on trials that have been identified

This review summarises current knowledge on inflammation and anti-inflammatory pharmacotherapy, with the goal of optimising clinical outcomes in inflammation-associated disorders

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