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Emerging evidence also indicates that the copper transporter ATP7B promotes cisplatin efflux and the secretion of sEVs in OSCC, thereby reducing the effective intracellular drug concentration, suppressing cuproptosis, and contributing to cisplatin resistance (55)

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"By strengthening oversight of imported APIs and cracking down on illegal drugs entering the U.S., we are taking aggressive action to protect consumers from poor-quality or dangerous GLP-1 drugs," said FDA Commissioner Marty Makary in the release